Baltimore Ravens at Tampa Bay Buccaneers (-3, 35.5)
In the past, Ravens head coach John Harbaugh usually played his starters for most of the first quarter but with a rash of injuries during the summer, Baltimore may limit the action of its first stringers.
Tampa Bay is also trying to protect its key players from injury this offseason. The Bucs aren’t sold on Josh Freeman as the No. 1, so there could be plenty of snaps for him and rookie QB Mike Glennon.
St. Louis Rams at Cleveland Browns (-4, 35.5)
St. Louis is going to give RB Daryl Richardson the starting gig heading into the preseason opener. The Rams will work in their new offensive line additions Thursday, so Sam Bradford’s workload could depend on the protection.
Cleveland won’t have RB Trent Richardson in the lineup versus St. Louis and is still without Montario Hardesty, leaving rushing duties to third and fourth-stringers Dion Lewis and Brandon Jackson.
Washington Redskins at Tennessee Titans (-2.5, 35.5)
While Robert Griffin III says he feels great, the Redskins won’t risk throwing their franchise QB out there Thursday. Washington will go with Kirk Cousins at QB and is expected to play its starters 10-15 plays.
Tennessee head coach Mike Munchak is focusing on his rebuilt offensive line this preseason, more specifically paving the way for RB Chris Johnson. The Titans first string will play between 18 and 25 plays.
Cincinnati Bengals at Atlanta Falcons (-2.5, 37)
These two teams have shared practice time the past week, so there may be some familiarity with each other Thursday. Bengals star WR A.J. Green will sit out while nursing a sore knee and fellow WR Andrew Hawkins is out with an ankle injury.
Atlanta won’t have TE Tony Gonzalez, WR Julio Jones or LB Sean Weatherspoon in Week 1 of the preseason. Head coach Mike Smith may not keep QB Matt Ryan under center long with injuries to the offensive line this week.
Denver Broncos at San Francisco 49ers (-3, 35)
Peyton Manning is expected to see limited action all preseason but he did tell reporters he was anxious to play the 49ers Thursday, hinting that he may actually take snaps Thursday. Manning didn’t play in Denver’s Week 1 preseason game last summer.
San Francisco will give its first stringers a taste of action before turning its attention to position needs. An injury to CB Chris Culliver has left a big hole in the secondary, so there could be plenty of tinkering with the pass defense. Colt McCoy will get some face time as Colin Kaepernick’s backup.
Seattle Seahawks at San Diego Chargers (+2, 35.5)
The Seahawks have become one of the best preseason bets, going 39-26-3 ATS since 1995 including a 4-0 ATS mark last summer. Seattle QB Russell Wilson, who will see limited snaps, told reporters the Seahawks are bringing a basic offense into Thursday game.
San Diego’s new head coach Mike McCoy is stressing speed this summer, so the Bolts could be full of juice Thursday night, even though they’re missing some downfield threats. The Chargers lost WR Danario Alexander for the season after he tore his ACL this week and WR Vincent Brown is still slowed with a hamstring strain.